Numerical simulation of Nitinol peripheral stents: from laser-cutting to deployment in a patient specific anatomy

The current clinical trend is to use percutaneous techniques, exploiting Nitinol self-expanding stents, to treat peripheral occluded vessels such as carotid or superficial femoral arteries. Although this class of stents addresses the biomechanical requirements (i.e. flexibility, kink resistance, etc.), it has been observed that many of these stents implanted in peripheral vessels are fractured. Numerical simulations have shown to be very useful in the investigation and optimization of stents and also to provide novel insights into fatigue/fracture mechanics. To date most finite element based stent simulations are performed in a straight simplified anatomy and neglect the actual deployment process; consequently there is a need for more realistic simulations taking into account the different stages of the stent design process and the insertion in the target anatomy into account. This study proposes a virtual framework to analyze numerically Nitinol stents from the laser-cutting stage to the deployment in a (patient specific) tortuous anatomy.